PDL1 (His Tag)
Human PD-L1 / B7-H1 Protein (His Tag)
靶点信息
分子别名（Synonym）
PD-L1, CD274, B7-H1, PDCD1L1, PDCD1LG1
背景信息 （Background）
Programmed cell death 1 ligand 1 (PDL1) is also known as B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1 and PDCD1LG1, which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses. PDL1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression.
产品信息
表达区间与表达系统（Source）
The product is expressed from human 293 cells (HEK293). It contains AA Met 1 - Arg 238 and 6x His tag at C-terminus.
Predicted N-terminus: Phe 19
蛋白编号（Accession）
标签（Tag）
C-6xHis
分子量（MW）
The protein has a predicted MW of 25 kDa. The protein migrates as 27 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
剂型（Formulation）
Liquid in HEPES buffer, pH 7.2.
内毒素（Endotoxin）
Less than 1.0 EU/ug by the LAL method.
纯度（Purity）
＞90% as determined by SDS-PAGE
存储（Storage）
This product is stable after storage at:
-70°C for 3 months under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.
运输 （Shipping）
The product is shipped at ambient temperature.
Upon receipt, store it immediately at -70℃.
